Integrated promoter and pathway analysis lies at the core of our approach to analyzing changes in gene or protein signatures in a cell as a consequence, for example, of disease pathogenesis. We are going to provide the X-Platform as a comprehensive, modularized system of "Bricks".
The core of this platform will be made freely available, and we invite all members of the scientific community to contribute their own building blocks, either for free or on a commercial basis. You are cordially invited to learn more about the geneXplain platform.
Particularly well suited for evaluating and visualizing results of genome and transcriptome research such as Next Generation Sequencing (NGS) approaches, are the tools IMC (in-silico Molecular Cloning) and GT (Genome Traveler). For these locally running program packages, we also offer turnkey solutions of pre-installed software.
It is our wish to contribute to state of the art systems biological research by offering a comprehensive view of molecular and genetic networks operating in and constituting human cells. Through our geneXplain platform, we are making available the world's largest collection of interactions and pathways, the GeneWays database, structured in a sophisticated way so that the contents will be of optimal use in systems biology.
In addition, this more static view is complemented by sophisticated approaches to simulate the dynamics of cellular and physiological processes. The first tools (Bricks) assisting in that have already been implemented in our platform.
In this field, based on the world's largest data collections pertaining to the biological activities of chemical compounds and their structures, PASS and PharmaExpert enable users to identify potential lead structures out of millions of chemical substances, thereby efficiently shortening development times for specific drugs or molecular probes for research purposes. Particularly valuable for experts is the program GUSAR, which enables construction of highly specific models based on own data sets.